The Senior Clinical Scientist will serve as a key scientific leader within Rune Labs, driving our research initiatives while acting as a bridge to the broader Parkinson's research community. This role combines deep scientific expertise in movement disorders with the ability to shape partnerships and influence stakeholders across pharma, academia, and patient advocacy organizations.

Key Responsibilities

Scientific Leadership:

- Lead analysis of Rune Labs' proprietary datasets to generate novel insights into Parkinson's disease progression and treatment response

- Design and oversee implementation of research initiatives using our high-frequency movement disorder data

- Collaborate with pharma partners to develop digital biomarkers and novel endpoints for clinical trials

- Author peer-reviewed publications and present at major scientific conferences

- Guide development of our clinical and scientific roadmap

- Provide scientific oversight for pharma partnerships and clinical validation studies

External Engagement:

- Serve as a scientific representative at key industry conferences and meetings

- Build and maintain relationships with key opinion leaders in movement disorders

- Engage with patient advocacy organizations on research initiatives

- Support business development team in technical discussions with pharma partners

- Participate in relevant academic and industry working groups

- Contribute to regulatory strategy and engagement

Research & Development:

- Guide development of novel analytics approaches for movement disorder data

- Collaborate with data science team on algorithm development and validation

- Support validation of digital biomarkers and clinical endpoints

- Design studies to evaluate real-world effectiveness of therapeutics

- Partner with product team to ensure scientific rigor in feature developmen

Required Qualifications

- PhD or MD in neuroscience, medicine, or related field

- 10+ years of experience in movement disorders research or clinical development

- Strong publication record in movement disorders

- Demonstrated expertise in clinical trial design and execution

- Advanced skills in data analysis and statistical methods

- Track record of successful collaboration with pharma industry

- Established relationships with key opinion leaders in movement disorders

- Possess current U.S. work authorization

Desired Experience

- Experience with digital health technologies or wearable devices

- Background in digital biomarker development

- Knowledge of FDA and EMA regulatory requirements

- Understanding of machine learning and AI applications in healthcare

- Experience with real-world evidence generation

- Track record of successful grant funding

Impact Areas

- Shape the scientific understanding of Parkinson's disease progression

- Influence the development of next-generation therapeutics

- Advance the field of digital biomarkers in movement disorders

- Build bridges between technology and traditional clinical research

- Support the validation of novel endpoints for clinical trials

Success Metrics

- Publication of high-impact research using Rune Labs data

- Development of validated digital biomarkers

- Establishment of new research partnerships

- Contribution to successful regulatory submissions

- Growth of Rune Labs' scientific reputation in the field

Compensation

- Base salary: $190,000 - $240,000

- Equity eligible

- Bonus target up to 30%

- Research conference and continuing education allowance

- Publication and speaking engagement support

- Comprehensive benefits package

Location

San Francisco Bay Area preferred; will consider remote for exceptional candidates